Comments on: Comparing the SN1 and SN2 Reactions https://www.masterorganicchemistry.com/2012/08/08/comparing-the-sn1-and-sn2-reactions/ Sat, 18 Apr 2026 10:56:35 +0000 hourly 1 https://wordpress.org/?v=6.9.4 By: Kritish Vyas https://www.masterorganicchemistry.com/2012/08/08/comparing-the-sn1-and-sn2-reactions/#comment-711373 Mon, 14 Oct 2024 19:52:47 +0000 https://www.masterorganicchemistry.com/?p=5454#comment-711373 Thanks for the sn1 and sn2 comparisons

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By: A https://www.masterorganicchemistry.com/2012/08/08/comparing-the-sn1-and-sn2-reactions/#comment-647631 Wed, 08 Feb 2023 17:09:10 +0000 https://www.masterorganicchemistry.com/?p=5454#comment-647631 Ah, I’m glad it isn’t the “hobo on the bench” analogy anymore, thanks for being considerate enough to change it to cats
I love how they use their tails to balance in the video!

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By: James Ashenhurst https://www.masterorganicchemistry.com/2012/08/08/comparing-the-sn1-and-sn2-reactions/#comment-566619 Tue, 08 Oct 2019 02:52:22 +0000 https://www.masterorganicchemistry.com/?p=5454#comment-566619 In reply to Sina riahi.

In SN1 reactions the rate limiting step is loss of leaving group to give a carbocation. Polar protic solvents have a higher dielectric constant and can stabilize the resulting carbocation species that results from ionization. Secondly, polar protic solvents are often the nucleophiles in these reactions and can be neutralized through deprotonation.
In SN2 reactions the rate limiting step is attack of the nucleophile at the alkyl halide. Using a polar aprotic solvent results in a more free nucleophile (free from hydrogen bonding) resulting in a higher reaction rate than if a polar protic solvent were used.

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By: Sina riahi https://www.masterorganicchemistry.com/2012/08/08/comparing-the-sn1-and-sn2-reactions/#comment-564365 Wed, 18 Sep 2019 13:35:16 +0000 https://www.masterorganicchemistry.com/?p=5454#comment-564365 Hi,thanks for the post. But here is question.why protic solvent are favored by SN1 and vice versa?

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By: James Ashenhurst https://www.masterorganicchemistry.com/2012/08/08/comparing-the-sn1-and-sn2-reactions/#comment-563230 Thu, 05 Sep 2019 17:04:46 +0000 https://www.masterorganicchemistry.com/?p=5454#comment-563230 In reply to Vineet.

If the substrate is primary, it will be SN2, since the reaction rate will be faster with a stronger nucleophile.

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By: Vineet https://www.masterorganicchemistry.com/2012/08/08/comparing-the-sn1-and-sn2-reactions/#comment-562398 Sat, 31 Aug 2019 17:49:40 +0000 https://www.masterorganicchemistry.com/?p=5454#comment-562398 What should i do when both strong and weak nucleophile are present in the reaction??? Should i proceed through SN1 OR SN2???

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By: James Ashenhurst https://www.masterorganicchemistry.com/2012/08/08/comparing-the-sn1-and-sn2-reactions/#comment-558636 Tue, 23 Jul 2019 03:00:27 +0000 https://www.masterorganicchemistry.com/?p=5454#comment-558636 In reply to Sanket.

Cool, thanks for letting me know Sanket. So what could be better about the site?

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By: Sanket https://www.masterorganicchemistry.com/2012/08/08/comparing-the-sn1-and-sn2-reactions/#comment-558434 Thu, 18 Jul 2019 18:36:06 +0000 https://www.masterorganicchemistry.com/?p=5454#comment-558434 Nicely Explained really impressed…
**Now, gaining confidence in organic chemistry**
THANK YOU ,
plzz make more blogs on organic chemistry thank you once again…

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By: Evangelin https://www.masterorganicchemistry.com/2012/08/08/comparing-the-sn1-and-sn2-reactions/#comment-553779 Mon, 22 Apr 2019 22:32:31 +0000 https://www.masterorganicchemistry.com/?p=5454#comment-553779 In reply to Pavan.

The stability of the tertiary carbon allows it to be a stronger carbocation compared to primary carbon which is very unstable as it the carbocation formed would be unstable. If the carbocation is unstable then it can just react in reverse with the leaving group and the reaction wouldn’t proceeed. So reactivity of SN1 reaction increases as the groups around carbon increase

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By: James Ashenhurst https://www.masterorganicchemistry.com/2012/08/08/comparing-the-sn1-and-sn2-reactions/#comment-547462 Sun, 10 Feb 2019 02:56:36 +0000 https://www.masterorganicchemistry.com/?p=5454#comment-547462 In reply to Michal.

Glad you found it useful Michal!

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