Comments on: Assigning Cahn-Ingold-Prelog (CIP) Priorities (2) – The Method of Dots https://www.masterorganicchemistry.com/2017/01/17/determining-rs-2-the-method-of-dots/ Thu, 07 May 2026 01:24:33 +0000 hourly 1 https://wordpress.org/?v=6.9.4 By: James Ashenhurst https://www.masterorganicchemistry.com/2017/01/17/determining-rs-2-the-method-of-dots/#comment-715998 Fri, 15 Nov 2024 21:12:38 +0000 https://www.masterorganicchemistry.com/?p=10347#comment-715998 In reply to Riddhi.

It’s definitely a chiral center.

]]> By: James Ashenhurst https://www.masterorganicchemistry.com/2017/01/17/determining-rs-2-the-method-of-dots/#comment-715997 Fri, 15 Nov 2024 21:12:11 +0000 https://www.masterorganicchemistry.com/?p=10347#comment-715997 In reply to Shri.

Yes it is (R). The sec-butyl has the highest priority, followed by vinyl and isopropyl with H being last. I will write this up as a conventional quiz. Thanks for mentioning!

]]> By: Shri https://www.masterorganicchemistry.com/2017/01/17/determining-rs-2-the-method-of-dots/#comment-715981 Fri, 15 Nov 2024 16:35:53 +0000 https://www.masterorganicchemistry.com/?p=10347#comment-715981 So what is the correct answer for the exercise under section 9? Is there a visual to show how the priorities can be assigned?
I got R as my answer, due to having to change the H position from planar to back view- is that correct?

]]> By: dharmendrakumar prajapati https://www.masterorganicchemistry.com/2017/01/17/determining-rs-2-the-method-of-dots/#comment-648654 Wed, 22 Feb 2023 04:29:10 +0000 https://www.masterorganicchemistry.com/?p=10347#comment-648654 Very nicely explained sir. Thank you for sharing it .

]]> By: Arpan Goswami https://www.masterorganicchemistry.com/2017/01/17/determining-rs-2-the-method-of-dots/#comment-599318 Sun, 28 Mar 2021 16:17:50 +0000 https://www.masterorganicchemistry.com/?p=10347#comment-599318 Thank you sir but I have a doubt. How will we determine the priority order if there is no clear hierarchy. For eg if one group is —C=O and other is —CH—Cl
| |
OH CH3
Here if we add phantom atom
Then the carboxylic acid group becomes
O Cl
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C—O and C—H
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OH CH3
So here how do we get the first point of difference because if O and H are compared then the oxygen should get higher priority but if O and Cl are compared Cl should get higher priority

]]> By: Rajprateem Nath https://www.masterorganicchemistry.com/2017/01/17/determining-rs-2-the-method-of-dots/#comment-598320 Sat, 27 Feb 2021 16:34:08 +0000 https://www.masterorganicchemistry.com/?p=10347#comment-598320 This was extremely helpful. Thanks!!

]]> By: Riddhi https://www.masterorganicchemistry.com/2017/01/17/determining-rs-2-the-method-of-dots/#comment-588904 Tue, 01 Dec 2020 15:00:05 +0000 https://www.masterorganicchemistry.com/?p=10347#comment-588904 Thanks sir for your informative article.
One thing I wanted to know was the answer of the given exercise question because I think it’s not a chiral centre.

]]> By: Harindu Kirihene https://www.masterorganicchemistry.com/2017/01/17/determining-rs-2-the-method-of-dots/#comment-581136 Fri, 12 Jun 2020 15:33:42 +0000 https://www.masterorganicchemistry.com/?p=10347#comment-581136 Thank you for providing this concise summary of CIP priorities which cleared away my doubts and resparked my interest in truly understanding chemistry concepts instead of simply memorizing them. I wish you all the best in future endeavors!

]]> By: Dipakchandra Sarkar https://www.masterorganicchemistry.com/2017/01/17/determining-rs-2-the-method-of-dots/#comment-580122 Tue, 12 May 2020 07:39:53 +0000 https://www.masterorganicchemistry.com/?p=10347#comment-580122 Nice presentation!

]]> By: rohit aggarwal https://www.masterorganicchemistry.com/2017/01/17/determining-rs-2-the-method-of-dots/#comment-571734 Wed, 27 Nov 2019 17:23:24 +0000 https://www.masterorganicchemistry.com/?p=10347#comment-571734 Thank you masterorganicchemistry for giving me wonderful information about methods of dots

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