Comments on: Free Radical Reactions https://www.masterorganicchemistry.com/2013/07/30/free-radical-reactions/ Wed, 05 Nov 2025 09:57:20 +0000 hourly 1 https://wordpress.org/?v=6.9.4 By: James Ashenhurst https://www.masterorganicchemistry.com/2013/07/30/free-radical-reactions/#comment-725014 Sun, 26 Jan 2025 11:45:44 +0000 https://www.masterorganicchemistry.com/?p=7428#comment-725014 In reply to Amjeet Pradesh.

You are correct. Typically to obtain a useful yield of the monochlorinated product you would have to have an extremely large excess of cyclohexane relative to chlorine and then separate out the product.

]]> By: Amjeet Pradesh https://www.masterorganicchemistry.com/2013/07/30/free-radical-reactions/#comment-724819 Fri, 24 Jan 2025 16:37:21 +0000 https://www.masterorganicchemistry.com/?p=7428#comment-724819 How come during radical halogenation of cyclohexane we’re always shown (e.g. in textbooks) the monohalogenated product? Wouldn’t overhalogenation be a problem, since the C-H-bonds in monochlorocyclohexane are (with exception of the C-Cl) bond very similar in terms of bond strength? Even if the product of the first halogenation may be less reactive than the starting material (which it barely is, presumably), the extreme reactivity of the halogen radicals would easily substitute the remaining hydrogens.

Sorry for the long question and thank you in advance!

]]> By: Nidhi Sharma https://www.masterorganicchemistry.com/2013/07/30/free-radical-reactions/#comment-601194 Fri, 21 May 2021 20:13:40 +0000 https://www.masterorganicchemistry.com/?p=7428#comment-601194 Wow, what an explanation…
Thanks a lot!

]]> By: Christian https://www.masterorganicchemistry.com/2013/07/30/free-radical-reactions/#comment-593334 Wed, 06 Jan 2021 17:36:50 +0000 https://www.masterorganicchemistry.com/?p=7428#comment-593334 Some radical mechanisms occur without the input of energy. How can I determine whether a reaction will proceed via a radical- or polar-mediated pathway?

]]> By: James Ashenhurst https://www.masterorganicchemistry.com/2013/07/30/free-radical-reactions/#comment-556345 Fri, 14 Jun 2019 17:23:19 +0000 https://www.masterorganicchemistry.com/?p=7428#comment-556345 In reply to Christine.

Come on, that shouldn’t take too much time to find the answer to.

]]> By: James Ashenhurst https://www.masterorganicchemistry.com/2013/07/30/free-radical-reactions/#comment-556344 Fri, 14 Jun 2019 17:22:46 +0000 https://www.masterorganicchemistry.com/?p=7428#comment-556344 In reply to rachit.

Neutral means that it bears no formal charge. Non-polar means that, to a good approximation, the molecule doesn’t have a significant dipole moment.

]]> By: James Ashenhurst https://www.masterorganicchemistry.com/2013/07/30/free-radical-reactions/#comment-556343 Fri, 14 Jun 2019 17:22:05 +0000 https://www.masterorganicchemistry.com/?p=7428#comment-556343 In reply to farzeen.

They are neutral. In most polar reactions there is an activation barrier for forming a charged species such as a carbocation which can be reduced through solvation with a polar solvent. Not the case here.

]]> By: farzeen https://www.masterorganicchemistry.com/2013/07/30/free-radical-reactions/#comment-511910 Fri, 28 Apr 2017 05:04:11 +0000 https://www.masterorganicchemistry.com/?p=7428#comment-511910 Hi James,
Free radical carbon atoms are electron deficient and they are stabilized by electron releasing groups next to it.
But why aren’t they stabilized by solvation?

]]> By: APALA SEN https://www.masterorganicchemistry.com/2013/07/30/free-radical-reactions/#comment-500552 Sat, 07 Jan 2017 13:51:35 +0000 https://www.masterorganicchemistry.com/?p=7428#comment-500552 Thank you for making a complex concept appear to be so trivial, something myriad books and study references have failed to do.

]]> By: rachit https://www.masterorganicchemistry.com/2013/07/30/free-radical-reactions/#comment-494446 Mon, 28 Nov 2016 13:52:06 +0000 https://www.masterorganicchemistry.com/?p=7428#comment-494446 is neutral and non polar not same?

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