Comments on: Electrophilic Aromatic Substitutions (1) – Halogenation of Benzene

By: Blessed siame

Blessed siame — Tue, 12 May 2026 04:10:40 +0000

Thank you very much for the information

By: James Ashenhurst

James Ashenhurst — Thu, 19 May 2022 19:55:18 +0000

In reply to Rajnikant. This would have to involve a phenyl radical intermediate. Phenyl radicals are known, and they can be made from (for example) aryl halides with reductants like tributyl tin hydride.

By: Rajnikant

Rajnikant — Wed, 18 May 2022 03:58:58 +0000

Can free radical substitution take pace on benzene?

By: James Ashenhurst

James Ashenhurst — Wed, 06 May 2020 02:27:01 +0000

In reply to Tal Parness. Any of the eight C-H bonds can undergo electrophilic aromatic substitution. Your task is to show that this results in only two distinct compounds.

By: Tal Parness

Tal Parness — Tue, 05 May 2020 19:10:59 +0000

how come naphthalene only has 2 derivatives? Shouldn’t there be a derivative on all the sp2 carbons?

By: Waseeq Ur Rehman

Waseeq Ur Rehman — Tue, 04 Feb 2020 14:31:23 +0000

useful material. Well done, thanks

By: Andrea

Andrea — Fri, 06 Dec 2019 08:20:14 +0000

Hi James! In this case if I use two equivalents of chlorine will I get a disubstituted benzene? Thanks

By: James

James — Tue, 23 Oct 2018 19:01:23 +0000

In reply to Evan.

One phenyl group is attached to a carbonyl (C=O). The other is attached to a CH2 attached to a carbonyl.

Which phenyl group is more activated? : – )

By: Evan

Evan — Thu, 28 Jun 2018 09:08:26 +0000

Hello, love the articles. I am studying for a test including this topic, was wondering where would the Bromine attack if there was a phenyl group attached to a ketone attached to a methyl group attached to another phenyl group. I believe it attaches to the phenyl group furthest from the ketone but was not sure.