Comments on: Cyclic Dienes and Dienophiles in the Diels-Alder Reaction https://www.masterorganicchemistry.com/2017/09/08/cyclic-dienes-and-dienophiles-in-the-diels-alder-reaction/ Tue, 28 Oct 2025 17:19:56 +0000 hourly 1 https://wordpress.org/?v=6.9.4 By: James Ashenhurst https://www.masterorganicchemistry.com/2017/09/08/cyclic-dienes-and-dienophiles-in-the-diels-alder-reaction/#comment-742175 Wed, 21 May 2025 19:23:31 +0000 https://www.masterorganicchemistry.com/?p=11016#comment-742175 In reply to Giulio.

I don’t know specifically which example you are referring to, but yes, the Diels-Alder reaction can be sensitive to steric effects.

One issue that comes up is how accessible the s-cis conformation is for the diene. When there is a substituent on the “inside” of the diene, the s-cis conformation becomes quite unfavorable and this slows the reaction down considerably.

]]> By: James Ashenhurst https://www.masterorganicchemistry.com/2017/09/08/cyclic-dienes-and-dienophiles-in-the-diels-alder-reaction/#comment-742174 Wed, 21 May 2025 19:20:36 +0000 https://www.masterorganicchemistry.com/?p=11016#comment-742174 In reply to Pat.

Thank you Pat

]]> By: Pat https://www.masterorganicchemistry.com/2017/09/08/cyclic-dienes-and-dienophiles-in-the-diels-alder-reaction/#comment-742169 Wed, 21 May 2025 18:06:21 +0000 https://www.masterorganicchemistry.com/?p=11016#comment-742169 If only you knew how much you help and save us! Thank you!

]]> By: salma said https://www.masterorganicchemistry.com/2017/09/08/cyclic-dienes-and-dienophiles-in-the-diels-alder-reaction/#comment-721249 Wed, 25 Dec 2024 19:05:43 +0000 https://www.masterorganicchemistry.com/?p=11016#comment-721249 ]]> thanks 🙏

]]> By: Grace✨ https://www.masterorganicchemistry.com/2017/09/08/cyclic-dienes-and-dienophiles-in-the-diels-alder-reaction/#comment-644307 Wed, 14 Dec 2022 07:36:08 +0000 https://www.masterorganicchemistry.com/?p=11016#comment-644307 🤩 Keep doing what you dooo!!! Lots of love!]]> You are a life saverrrrrr🤭🤩
Keep doing what you dooo!!!
Lots of love!

]]> By: HEMRAJ MEENA https://www.masterorganicchemistry.com/2017/09/08/cyclic-dienes-and-dienophiles-in-the-diels-alder-reaction/#comment-630896 Tue, 21 Jun 2022 02:26:52 +0000 https://www.masterorganicchemistry.com/?p=11016#comment-630896 coool cooooooool explantion and examples thank you so much

]]> By: James Ashenhurst https://www.masterorganicchemistry.com/2017/09/08/cyclic-dienes-and-dienophiles-in-the-diels-alder-reaction/#comment-620685 Tue, 15 Feb 2022 03:11:38 +0000 https://www.masterorganicchemistry.com/?p=11016#comment-620685 In reply to Emily.

So glad to hear that! Keep up the great work, Emily!

]]> By: Emily https://www.masterorganicchemistry.com/2017/09/08/cyclic-dienes-and-dienophiles-in-the-diels-alder-reaction/#comment-620366 Fri, 11 Feb 2022 21:38:52 +0000 https://www.masterorganicchemistry.com/?p=11016#comment-620366 Thanks! Your website helped me get an ‘A’ in organic chemistry one, and is empowering me through organic chemistry two as well!

]]> By: Wilfred Kipkogei https://www.masterorganicchemistry.com/2017/09/08/cyclic-dienes-and-dienophiles-in-the-diels-alder-reaction/#comment-611631 Mon, 08 Nov 2021 11:59:07 +0000 https://www.masterorganicchemistry.com/?p=11016#comment-611631 Wow, I found this website and now I understand Diels alder reactions.

]]> By: James Ashenhurst https://www.masterorganicchemistry.com/2017/09/08/cyclic-dienes-and-dienophiles-in-the-diels-alder-reaction/#comment-607241 Tue, 19 Oct 2021 16:08:02 +0000 https://www.masterorganicchemistry.com/?p=11016#comment-607241 In reply to Zainab.

I am glad you find it useful, Zainab.

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